As we move toward the third decade of the 21st century, Christians concerned with defending the right to life face daunting new challenges. To protect fellow humans against emerging threats, we must re-examine the effectiveness of our most fundamental strategies. The following essays serve as a critical contribution to the conversation among individuals and organizations who, as diverse as they may be, are unified on the biblical principles of the sanctity of human life and human dignity for all those created in the image of God--without exception and without compromise.