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The Emperor of All Maladies: A Biography of Cancer (2010)

por Siddhartha Mukherjee

Outros autores: Ver a secção outros autores.

MembrosCríticasPopularidadeAvaliação médiaDiscussões / Menções
5,0221962,172 (4.3)1 / 340
A "biography" of cancer from its origins to the epic battle to cure, control, and conquer it. A combination of medical history, cutting-edge science, and narrative journalism that transforms the listener's understanding of cancer and much of the world around them. The author provides a glimpse into the future of cancer treatments and offers a bold new perspective on the way doctors, scientists, philosophers, and lay people have observed and understood the human body for millennia.… (mais)
  1. 42
    The Secret History of the War on Cancer por Devra Davis (lemontwist)
  2. 21
    Illness as Metaphor & AIDS and Its Metaphors por Susan Sontag (caitlinlizzy)
  3. 10
    And the Band Played On: Politics, People, and the AIDS Epidemic por Randy Shilts (DetailMuse)
    DetailMuse: Both are excellent history-of-medicine narratives.
  4. 00
    Grace and Grit: Spirituality and Healing in the Life and Death of Treya Killam Wilber por Ken Wilber (wester)
    wester: A time-slice of cancer history in a personal story, versus the overview of this same history. Close up and panorama view of the same thing.
  5. 00
    The Philadelphia Chromosome: A Mutant Gene and the Quest to Cure Cancer at the Genetic Level por Jessica Wapner (hailelib)
    hailelib: Expands on Mukherjee's discussion of the development and testing of Gleevec.
  6. 00
    p53: The Gene that Cracked the Cancer Code por Sue Armstrong (rodneyvc)
  7. 00
    Last Night in the OR: A Transplant Surgeon's Odyssey por Bud Shaw (JenniferRobb)
    JenniferRobb: Last Night in the OR discusses early liver transplants; The Emperor of All Maladies details the evolution of cancer treatment
  8. 01
    The Gene: An Intimate History por Siddhartha Mukherjee (jigarpatel)
    jigarpatel: Given the relationship between cancer and genetic pathways, Mukherjee's later The Gene (2016) is insightful for the layperson, recommend this as a precursor to The Emperor of All Maladies.
  9. 02
    The Wisdom of the Body: Discovering the Human Spirit por Sherwin B. Nuland (fountainoverflows)
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Grupo TópicoMessagensÚltima Mensagem 
 Science!: Emperor of Maladies-- book about cancer6 não lido / 6kirahelm, Julho 2012

» Ver também 340 menções

Inglês (191)  Espanhol (1)  Alemão (1)  Holandês (1)  Italiano (1)  Todas as línguas (195)
Mostrando 1-5 de 195 (seguinte | mostrar todos)
4.5 stars ( )
  EllieBhurrut | Jan 24, 2024 |
You know the feeling that you get when you're done reading a book on the subject and realize how it changed your understanding of the field dramatically? Such as Feynman's Lectures on Physics, A Brief History of Time, or The Emperor's New Mind? This magnificent treatise on cancer is just what the subject needed - a meticulous, no-holds-barred treatment that reveals a plethora of information on cancer, and our ancient, never-ending war with it - a constantly shape-shifting enemy whose root is ourselves.
Mukherjee describes in eye-watering detail how our understanding of cancer has changed in around four thousand years, and how the landscape of the 'War Against Cancer' has undergone multiple paradigm shifts - from the witch-doctors who thought the best cure for the then-unnamed disease was crab soup; to current efforts, which are a mixture of chemotherapy and targeted drugs, some of which can almost erase certain cancers from its roots.
Absolutely no detail is withheld from the reader - the politics, the money, the legal battles over potential cures and clinical trials, the innumerable doctors involved, the patients whose lives were altered with the onset of the disease, and how each potential drug worked (or why it stopped working).
Mukherjee also focuses on how patients embrace their sickness as the new normal, and how some patients accept death easier than doctors - his work is, above all, a testimony to the tenacity and resilience of the human spirit.
In conclusion, although this might not be the most readable book, it is definitely one of the most sobering books I have ever encountered. A must-read. ( )
  SidKhanooja | Sep 1, 2023 |
Great book. It's very helpful for anyone who is a caregiver or is afflicted with Cancer. It gave me a new perspective as a caregiver/ It is very detailed and requires some work to read and understand. ( )
  Michael_Lilly | Aug 7, 2023 |
The book starts out rooted firmly in the human experience, told through the stories of patients, doctors, and discoverers from the ancients up through the modern era. I found these stories fascinating and often incredibly sad; I could relate to them. Around the 1960s the book shifts into a more technical vein, which makes sense because this is when so many innovations in cancer research and treatment began, but I found myself disengaging from the story. The author does a laudable job of keeping the human experience a part of the story, but this is a biography of cancer - not humans - and at some point the story becomes less about "us" and more about "it". Or rather, "them", because one of the most fascinating parts of the book was seeing how heterogenous cancer is in the human body. Lymphomas are completely different from breast cancer, which is completely different from sarcoma, etc. I truly had no idea.

Also fascinating was how breast cancer was the focus of cancer research for literally hundreds of years. This seems like a woman-positive situation until you discover the devastating surgeries and experiments that doctors inflicted on the female body. Would they have been so quick to carve out literal pounds of flesh if these were male bodies? Would male patients have had more authority over their own care, and been fully informed about what was about to be done to their bodies? Kudos to the author for explicitly calling out the medical industry on its historically cavalier treatment of women, and acknowledging the women of the 1970s who refused to be sidelined in their own treatment, and thus forged the patients' rights movement out of the second-wave feminist movement. ( )
  blueskygreentrees | Jul 30, 2023 |
Me tomó varios meses leer este libro, varios de ellos mientras convivía con una persona muy cercana, enferma de cáncer. Entonces, me costó mucho trabajo, tanto que tuve que dejarlo en espera un par de meses.

Ahora que he vuelto a él, lo encuentro un libro súper intenso por los casos de estudio, por las metáforas, por las explicaciones y la información científica (que además es bastante accesible a un lector sin conocimiento de medicina, biología, química o todas las disciplinas que se unen para luchar contra esta enfermedad).

Me quedo con un fragmento casi al final del libro que creo resume esta lectura: "La mejor manera de 'ganar' la guerra contra el cáncer consiste, quizás, en redefinir la victoria". ( )
  uvejota | Jul 26, 2023 |
Mostrando 1-5 de 195 (seguinte | mostrar todos)
It's time to welcome a new star in the constellation of great doctor-writers. With this fat, enthralling, juicy, scholarly, wonderfully written history of cancer, Siddhartha Mukherjee - a cancer physician and researcher at Columbia University - vaults into that exalted company ...
adicionada por tim.taylor | editarThe Washington Post, Susan Okie (Nov 21, 2010)
 

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Nome do autorPapelTipo de autorObra?Estado
Siddhartha Mukherjeeautor principaltodas as ediçõescalculado
Hoye, StephenNarradorautor secundárioalgumas ediçõesconfirmado

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Illness is the night-side of life, a more onerous citizenship. Everyone who is born holds dual citizenship, in the kingdom of the well and the kingdom of the sick. Although we all prefer to use only the good passport, sooner or later each of us is obliged, at least for a spell, to identify ourselves as citizens of that other place. —Susan Sontag
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On the morning of May 19, 2004, Carla Reed, a thirty-year-old kindergarten teacher from Ipswich, Massachusetts, a mother of three young children, woke up in bed with a headache.
In a damp fourteen-by-twenty-foot laboratory in Boston on a December morning in 1947, a man named Sidney Farber waited impatiently for the arrival of a parcel from New York.
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Physicians of the utmost fame Were called at once; but when they came They answered, as they took their Fees, "There is no Cure for this Disease." —Hilaire Belloc
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A "biography" of cancer from its origins to the epic battle to cure, control, and conquer it. A combination of medical history, cutting-edge science, and narrative journalism that transforms the listener's understanding of cancer and much of the world around them. The author provides a glimpse into the future of cancer treatments and offers a bold new perspective on the way doctors, scientists, philosophers, and lay people have observed and understood the human body for millennia.

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