Juvenile Fiction. Juvenile Literature. Best Buddies introduces a boy-and-dog duo who are BEST FRIENDS and who do EVERYTHING together! So how will they manage being apart when the boy heads to school for the first time? Find out how a clever boy with Down syndrome and his loyal pet find the perfect way to feel close even when they can't be together. A sweet, inspiring story that will ease concerns about the first day of school and other big changes for kids.